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KDM5A-IN-1 [1905481-36-8]

Research Use Only
HY-100014
MedChem Express
CAS Number1905481-36-8
Product group Chemicals
Estimated Purity95.71%
Molecular Weight290.36
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    KDM5A-IN-1 [1905481-36-8]
  • Delivery Days Customer
    10
  • CAS Number
    1905481-36-8
  • Certification
    Research Use Only
  • Estimated Purity
    95.71%
  • Molecular Formula
    C15H22N4O2
  • Molecular Weight
    290.36
  • Scientific Description
    KDM5A-IN-1 is a potent, orally bioavailable pan-histone lysine demethylases 5 (KDM5) inhibitor with IC50s of 45 nM, 56 nM and 55 nM for KDM5A, KDM5B and KDM5C, respectively, and with an EC50 value of 960 nM for PC9 H3K4Me3. KDM5A-IN-1 is significantly less potent against other KDM5B enzymes (1A, 2B, 3B, 4C, 6A, 7B).
  • SMILES
    O=C(C1CC1)N[C@@H]2CCN(C(C3=CC(C(C)C)=NN3)=O)C2
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200