KDM5A-IN-1 [1905481-36-8]
HY-100014
CAS Number1905481-36-8
Product group Chemicals
Estimated Purity95.71%
Molecular Weight290.36
Overview
- SupplierMedChem Express
- Product NameKDM5A-IN-1 [1905481-36-8]
- Delivery Days Customer10
- CAS Number1905481-36-8
- CertificationResearch Use Only
- Estimated Purity95.71%
- Molecular FormulaC15H22N4O2
- Molecular Weight290.36
- Scientific DescriptionKDM5A-IN-1 is a potent, orally bioavailable pan-histone lysine demethylases 5 (KDM5) inhibitor with IC50s of 45 nM, 56 nM and 55 nM for KDM5A, KDM5B and KDM5C, respectively, and with an EC50 value of 960 nM for PC9 H3K4Me3. KDM5A-IN-1 is significantly less potent against other KDM5B enzymes (1A, 2B, 3B, 4C, 6A, 7B).
- SMILESO=C(C1CC1)N[C@@H]2CCN(C(C3=CC(C(C)C)=NN3)=O)C2
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200