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ProductsBack/Ketanserin . tartrate [83846-83-7]
Chemical Structure
Chemical Structure
Chemical Structure

Ketanserin . tartrate [83846-83-7]

Research Use Only
AG-CR1-0014
AdipoGen Life Sciences
Estimated Purity>98% (NMR)
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Product group Chemicals
Molecular Weight395.4 . 150.1
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    Ketanserin . tartrate [83846-83-7]
  • Delivery Days Customer
    10
  • ADR Class
    6.1
  • Certification
    Research Use Only
  • Estimated Purity
    >98% (NMR)
  • Hazard Information
    Danger,Excepted quantity
  • Molecular Formula
    C22H22FN3O3 . C4H6O6
  • Molecular Weight
    395.4 . 150.1
  • Scientific Description
    Chemical. CAS: 83846-83-7. Formula: C22H22FN3O3 . C4H6O6. MW: 395.4 . 150.1. Selective 5-HT2A serotonin receptor antagonist. ATP-sensitive potassium channel inhibitor. hERG potassium channel blocker. - Selective 5-HT2A serotonin receptor antagonist [1]. ATP-sensitive potassium channel inhibitor [2]. hERG potassium channel blocker [3].
  • SMILES
    [CH2]C#CC.OOOOOO.FC1=CC=C(C=C1)C(=O)C1CCN(CCN2C(=O)NC3=CC=CC=C3C2=O)CC1
  • Storage Instruction
    2°C to 8°C
  • UN Number
    UN 2811
  • UNSPSC
    12352200

References

  • Vascular activity of ketanserin (R 41 468), a selective 5-HT2 receptor antagonist: J.M. van Nueten, et al.; Arch. Int. Pharmacodyn. Ther. 250, 328 (1981)
  • Ketanserin, a 5-HT2 antagonist, directly inhibits the ATP-sensitive potassium channel in mouse ventricular myocytes: J.M. Ju, et al.; J. Cardiovasc. Pharmacol. 47, 96 (2006)
  • The 5-HT2 antagonist ketanserin is an open channel blocker of human cardiac ether-a-go-go-related gene (hERG) potassium channels: Q. Li, et al.; Br. J. Pharmacol. 155, 365 (2008)