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KHK-IN-1 hydrochloride [1303470-48-5]

Research Use Only
HY-12841A
MedChem Express
CAS Number1303470-48-5
Product group Chemicals
Estimated Purity98.05%
Molecular Weight459.01
Price on request
Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    KHK-IN-1 hydrochloride [1303470-48-5]
  • Delivery Days Customer
    10
  • CAS Number
    1303470-48-5
  • Certification
    Research Use Only
  • Estimated Purity
    98.05%
  • Molecular Formula
    C21H27ClN8S
  • Molecular Weight
    459.01
  • Scientific Description
    KHK-IN-1 hydrochloride (compound 8) is a selective and cell membrane permeable ketohexokinase (KHK) inhibitor (IC50=12 nM; F=34%). KHK-IN-1 hydrochloride inhibits the production of F1P in HepG2 cell lysates (IC>sub>50=400 nM). KHK-IN-1 hydrochloride has potential for the study of diabetes and obesity.
  • SMILES
    [H]Cl.CSC(C=CC=C1)=C1NC2=NC(N3CCNCC3)=NC4=C2N=CN=C4NCC5CC5
  • Storage Instruction
    -20°C,-80°C
  • UNSPSC
    12352200