L-NIO dihydrochloride [159190-44-0]

MedChem Express

L-NIO dihydrochloride [159190-44-0]

10

159190-44-0

95%

C7H17Cl2N3O2

246.13

L-NIO dihydrochloride is a potent, non-selective and NADPH-dependent nitric oxide synthase (NOS) inhibitor, with Kis of 1.7, 3.9, 3.9 microM for neuronal (nNOS), endothelial (eNOS), and inducible (iNOS), respectively. L-NIO dihydrochloride induces a consistentfocal ischemic infarctin rats.

N[C@@H](CCCNC(C)=N)C(O)=O.[H]Cl.[H]Cl

-20°C,-80°C

12352200