Lapatinib ditosylate [388082-77-7]

MedChem Express

Lapatinib ditosylate [388082-77-7]

10

388082-77-7

Research Use Only

98%

C43H42ClFN4O10S3

925.46

Lapatinib ditosylate (GW572016 ditosylate) is a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively.

O=S(CCNCC1=CC=C(C2=CC=C3C(C(NC4=CC(Cl)=C(C=C4)OCC5=CC(F)=CC=C5)=NC=N3)=C2)O1)(C)=O.O=S(C6=CC=C(C)C=C6)(O)=O.O=S(C7=CC=C(C)C=C7)(O)=O

2°C to 8°C,-20°C,-80°C

12352200