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ProductsBack/Lariatin A [732286-09-8]
Chemical Structure
Chemical Structure
Chemical Structure

Lariatin A [732286-09-8]

Research Use Only
AG-CN2-0120
AdipoGen Life Sciences
CAS Number732286-09-8
DownloadDatasheet
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Product group Chemicals
Estimated Purity>95% (HPLC)
Molecular Weight2051.4
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    Lariatin A [732286-09-8]
  • Delivery Days Customer
    10
  • CAS Number
    732286-09-8
  • Certification
    Research Use Only
  • Estimated Purity
    >95% (HPLC)
  • Hazard Information
    Non-hazardous,Warning
  • Molecular Formula
    C94H143N27O25
  • Molecular Weight
    2051.4
  • Scientific Description
    Chemical. CAS: 732286-09-8. Formula: C94H143N27O25. MW: 2051.4. Isolated from Rhodococcus jostii. Peptide with lasso structure. Antimycobacterial. - Peptide with lasso structure. Antimycobacterial.
  • SMILES
    [H]N([C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(O)=O)C(=O)C1CCC(=O)N([H])CC(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N([H])[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC2=CC=C(O)C=C2)C(=O)N[C@H](CCCNC(N)=N)C(=O)N1
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352200

References

  • Lariatins, antimycobacterial peptides produced by Rhodococcus sp. K01-B0171, have a lasso structure: M. Iwatsuki, et al.; JACS 128, 7486 (2006)
  • Lariatins, novel anti-mycobacterial peptides with a lasso structure, produced by Rhodococcus jostii K01-B0171: M. Iwatsuki, et al.; J. Antibiot. (Tokyo) 60, 357 (2007)
  • Lys17 in the 'lasso' peptide lariatin A is responsible for anti-mycobacterial activity: M. Iwatsuki, et al.; Bioorg. Med. Chem. Lett. 19, 2888 (2009)
  • Molecular cloning of the gene cluster for lariatin biosynthesis of Rhodococcus jostii K01-B0171: J. Inokoshi, et al.; Appl. Microbiol. Biotechnol. 95, 451 (2012)