Latrunculin B [76343-94-7]

AdipoGen Life Sciences

Latrunculin B [76343-94-7]

10

76343-94-7

Research Use Only

>96% (HPLC)

Non-hazardous,Warning

C20H29NO5S

395.5

Cell permeable marine toxin [1]. Disrupts microfilament-mediated processes [2]. Actin polymerization inhibitor in vitro and in vivo by the formation of a 1:1 complex with monomeric G-actin [1, 2, 3]. Depolymerizes actin filaments (F-actin) [3]. Less potent than Latrunculin A (Prod. No. AG-CN2-0027 http://www.adipogen.com/ag-cn2-0027/latrunculin-a.html ). May have fewer unwanted effects than latrunculin A and may be preferred for short-term studies [4, 5]. Acts via a different mechanism than cytochalasins. - Chemical. CAS: 76343-94-7. Formula: C20H29NO5S. MW: 395.5. Isolated from Latrunculia magnifica. Cell permeable marine toxin. Disrupts microfilament-mediated processes. Actin polymerization inhibitor in vitro and in vivo by the formation of a 1:1 complex with monomeric G-actin. Depolymerizes actin filaments (F-actin). Less potent than Latrunculin A (Prod. No. AG-CN2-0027 http://www.adipogen.com/ag-cn2-0027/latrunculin-a.html ). May have fewer unwanted effects than latrunculin A and may be preferred for short-term studies. Acts via a different mechanism than cytochalasins.

C[C@@H](CC[C@@H](O[C@]([C@@]1([H])NC(SC1)=O)(O)C2)C[C@H]2O3)/C=C\CC/C(C)=C\C3=O

2°C to 8°C,-20°C

12352200