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Ceritinib [1032900-25-6]

Research Use Only
HY-15656
MedChem Express
CAS Number1032900-25-6
Product group Chemicals
Estimated Purity97.21%
Molecular Weight558.14
Price on request
Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Ceritinib [1032900-25-6]
  • Delivery Days Customer
    10
  • CAS Number
    1032900-25-6
  • Certification
    Research Use Only
  • Estimated Purity
    97.21%
  • Molecular Formula
    C28H36ClN5O3S
  • Molecular Weight
    558.14
  • Scientific Description
    Ceritinib (LDK378) is a selective, orally bioavailable, and ATP-competitive ALK tyrosine kinase inhibitor with an IC50 of 200 pM. Ceritinib (LDK378) also inhibits IGF-1R, InsR, and STK22D with IC50 values of 8, 7, and 23 nM, respectively. Ceritinib (LDK378) shows great antitumor potency.
  • SMILES
    CC(C)OC1=CC(C2CCNCC2)=C(C)C=C1NC3=NC=C(Cl)C(NC4=CC=CC=C4S(=O)(C(C)C)=O)=N3
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200