LDN-214117 [1627503-67-6]
HY-16712
CAS Number1627503-67-6
Product group Chemicals
Estimated Purity98.74%
Molecular Weight419.52
Overview
- SupplierMedChem Express
- Product NameLDN-214117 [1627503-67-6]
- Delivery Days Customer10
- CAS Number1627503-67-6
- CertificationResearch Use Only
- Estimated Purity98.74%
- Molecular FormulaC25H29N3O3
- Molecular Weight419.52
- Scientific DescriptionLDN-214117 is an orally active ALK2 inhibitor with well-tolerated and good brain penetration. LDN-214117 has a high selectivity and low cytotoxicity for ALK2 with an IC50 value of 24 nM. LDN-214117 also is a specific bone morphogenetic proteins (BMPs) signaling inhibitor and has relatively selective inhibition for BMP6 with an IC50 value of 100 nM. LDN-214117 can be used for the research of fibrodysplasia ossificans progressiva (FOP), diffuse intrinsic pontine glioma (DIPG) [2]
- SMILESCC(C(C1=CC(OC)=C(OC)C(OC)=C1)=C2)=NC=C2C3=CC=C(N4CCNCC4)C=C3
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200