LDN-57444 [668467-91-2]

MedChem Express

LDN-57444 [668467-91-2]

10

668467-91-2

Research Use Only

95%

C17H11Cl3N2O3

397.64

LDN-57444 is a reversible, competitive and site-directed inhibitor of ubiquitin C-terminal hydrolase L1 (UCH-L1), with an IC50 of 0.88 microM and a Ki of 0.40 microM; LDN-57444 also suppresses UCH-L3 activity, with an IC50 of 25 microM.

O=C1N(CC2=CC(Cl)=CC=C2Cl)C3=C(C=C(Cl)C=C3)/C1=N/OC(C)=O

2°C to 8°C,-20°C,-80°C

12352200