Ribociclib hydrochloride [1211443-80-9]

MedChem Express

Ribociclib hydrochloride [1211443-80-9]

10

1211443-80-9

Research Use Only

99.2%

C23H31ClN8O

471.0

Ribociclib hydrochloride (LEE011 hydrochloride) is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex.

O=C(N(C)C)C(N1C2CCCC2)=CC(C1=N3)=CN=C3NC(N=C4)=CC=C4N5CCNCC5.Cl

2°C to 8°C,-20°C,-80°C

12352200