Bio-Connect

Lenalidomide (CC-5013) [191732-72-6]

Research Use Only
S1029
Selleck Chemicals
Product group Chemicals
Price on request
Packing Size
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Overview

  • Supplier
    Selleck Chemicals
  • Product Name
    Lenalidomide (CC-5013) [191732-72-6]
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Scientific Description
    Lenalidomide (CC-5013) is a TNF-alfa secretion inhibitor with IC50 of 13 nM in PBMCs. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide promotes cleaved caspase-3 expression and inhibit VEGF expression and induces apoptosis.
  • UNSPSC
    12352200