Lifitegrast [1025967-78-5]
HY-19344
CAS Number1025967-78-5
Product group Chemicals
Estimated Purity99.09%
Molecular Weight615.48
Overview
- SupplierMedChem Express
- Product NameLifitegrast [1025967-78-5]
- Delivery Days Customer10
- CAS Number1025967-78-5
- Estimated Purity99.09%
- Molecular FormulaC29H24Cl2N2O7S
- Molecular Weight615.48
- Scientific DescriptionLifitegrast (SAR 1118) is a potent integrin antagonist. Lifitegrast blocks the binding of intercellular adhesion molecule 1 (ICAM-1) to lymphocyte function-associated antigen 1 (LFA-1), interrupting the T cell-mediated inflammatory cycle. Lifitegrast inhibits Jurkat T cell attachment to ICAM-1 with an IC50 of 2.98 nM. Lifitegrast can be used for researching dry eye disease.
- SMILESO=C(O)[C@H](CC1=CC=CC(S(=O)(C)=O)=C1)NC(C2=C(Cl)C3=C(CN(C(C4=CC=C5C=COC5=C4)=O)CC3)C=C2Cl)=O
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200