Linifanib [796967-16-3]
HY-50751
Overview
- SupplierMedChem Express
- Product NameLinifanib [796967-16-3]
- Delivery Days Customer10
- CAS Number796967-16-3
- CertificationResearch Use Only
- Estimated Purity98.3%
- Molecular FormulaC21H18FN5O
- Molecular Weight375.4
- Scientific DescriptionLinifanib (ABT-869) is a potent and orally active multi-target inhibitor of VEGFR and PDGFR family with IC50s of 4, 3, 66, and 4 nM for KDR, FLT1, PDGFRbeta, and FLT3, respectively. Linifanib shows prominent antitumor activity. Linifanib has much less activity against unrelated RTKs, soluble tyrosine kinases, or serine/threonine kinases. Linifanib is a specific miR-10b inhibitor that blocks miR-10b biogenesis.
- SMILESO=C(NC1=CC=C(C2=C3C(N)=NNC3=CC=C2)C=C1)NC4=C(C=CC(C)=C4)F
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200