Linifanib (ABT-869) [796967-16-3]
S1003
Overview
- SupplierSelleck Chemicals
- Product NameLinifanib (ABT-869) [796967-16-3]
- Delivery Days Customer9
- CAS Number796967-16-3
- CertificationResearch Use Only
- Scientific DescriptionLinifanib (ABT-869, AL39324, RG3635) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR, CSF-1R, Flt-1/3 and PDGFRbèta with IC50 of 4 nM, 3 nM, 3 nM/4 nM and 66 nM respectively, mostly effective in mutant kinase-dependent cancer cells (i.e. FLT3). Linifanib (ABT-869) induces autophagy and apoptosis. Phase 3.
- UNSPSC12352200