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Linsitinib, Free Base [867160-71-2]

Research Use Only
ORB153620
Biorbyt
CAS Number867160-71-2
Product group Chemicals
Estimated Purity>99%
Molecular Weight421.49 g/mol
Price on request
Packing Size
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Overview

  • Supplier
    Biorbyt
  • Product Name
    Linsitinib, Free Base [867160-71-2]
  • Delivery Days Customer
    16
  • CAS Number
    867160-71-2
  • Certification
    Research Use Only
  • Estimated Purity
    >99%
  • Molecular Formula
    C26H23N5O
  • Molecular Weight
    421.49 g/mol
  • Scientific Description
    Linsitinib, Free Base. Linsitinib is also known as OSI-906, is a novel, potent small-molecule dual insulin-like growth factor-1 receptor (IGF-1R)/insulin receptor (IR) kinase inhibitor. Linsitinib inhibited IGF-1R and IR kinases with IC50 values of 35 nM and 75 nM, respectively. Linsitinib showed superior efficacy compared with MAB391, a selective anti-IGF-1R antibody, in human tumor xenograft models in which both IGF-1R and IR were phosphorylated.
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352200