Linsitinib, Free Base [867160-71-2]
ORB153620
CAS Number867160-71-2
Product group Chemicals
Estimated Purity>99%
Molecular Weight421.49 g/mol
Overview
- SupplierBiorbyt
- Product NameLinsitinib, Free Base [867160-71-2]
- Delivery Days Customer16
- CAS Number867160-71-2
- CertificationResearch Use Only
- Estimated Purity>99%
- Molecular FormulaC26H23N5O
- Molecular Weight421.49 g/mol
- Scientific DescriptionLinsitinib, Free Base. Linsitinib is also known as OSI-906, is a novel, potent small-molecule dual insulin-like growth factor-1 receptor (IGF-1R)/insulin receptor (IR) kinase inhibitor. Linsitinib inhibited IGF-1R and IR kinases with IC50 values of 35 nM and 75 nM, respectively. Linsitinib showed superior efficacy compared with MAB391, a selective anti-IGF-1R antibody, in human tumor xenograft models in which both IGF-1R and IR were phosphorylated.
- Storage Instruction-20°C or -80°C
- UNSPSC12352200