LJI308 [1627709-94-7]
HY-19713
CAS Number1627709-94-7
Product group Chemicals
Estimated Purity99.21%
Molecular Weight368.38
Overview
- SupplierMedChem Express
- Product NameLJI308 [1627709-94-7]
- Delivery Days Customer10
- CAS Number1627709-94-7
- CertificationResearch Use Only
- Estimated Purity99.21%
- Molecular FormulaC21H18F2N2O2
- Molecular Weight368.38
- Scientific DescriptionLJI308 is a potent pan-ribosomal S6 kinase (RSK) inhibitor, with IC50s of 6 nM, 4 nM, and 13 nM for RSK1, RSK2, and RSK3, respectively. LJI308 inhibits the phosphorylation of RSK (T359/S363) and YB-1 (S102) after irradiation, treatment with EGF, and in cells expressing a KRAS mutation.
- SMILESOC1=C(F)C=C(C2=C(C3=CC=C(N4CCOCC4)C=C3)C=CN=C2)C=C1F
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200