Lonafarnib [193275-84-2]

MedChem Express

Lonafarnib [193275-84-2]

10

193275-84-2

Research Use Only

98.05%

C27H31Br2ClN4O2

638.82

Lonafarnib (Sch66336) is a potent and orally active farnesyl transferase (FTase) inhibitor. Lonafarnib inhibits the activities of H-ras, K-ras and N-ras with IC50 values of 1.9 nM, 5.2 nM and 2.8 nM, respectively. Lonafarnib also has anti-hepatitis delta virus (HDV) activities.

O=C(N1CCC(CC(N2CCC([C@@H]3C4=C(Br)C=C(Cl)C=C4CCC5=CC(Br)=CN=C53)CC2)=O)CC1)N

2°C to 8°C,-20°C,-80°C

12352200