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Lopinavir [192725-17-0]

Research Use Only
HY-14588
MedChem Express
CAS Number192725-17-0
Product group Chemicals
Estimated Purity99.81%
Molecular Weight628.8
Price on request
Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Lopinavir [192725-17-0]
  • Delivery Days Customer
    10
  • CAS Number
    192725-17-0
  • Certification
    Research Use Only
  • Estimated Purity
    99.81%
  • Molecular Formula
    C37H48N4O5
  • Molecular Weight
    628.8
  • Scientific Description
    Lopinavir (ABT-378) is a highly potent, selective peptidomimetic inhibitor of the HIV-1 protease, with Kis of 1.3 to 3.6 pM for wild-type and mutant HIV protease. Lopinavir acts by arresting maturation of HIV-1 thereby blocking its infectivity. Lopinavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 14.2 microM.
  • SMILES
    CC1=C(OCC(N[C@@H](CC2=CC=CC=C2)[C@@H](O)C[C@H](CC3=CC=CC=C3)NC([C@H](C(C)C)N4C(NCCC4)=O)=O)=O)C(C)=CC=C1
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200