Darovasertib [1874276-76-2]

MedChem Express

Darovasertib [1874276-76-2]

10

1874276-76-2

99.42%

C22H23F3N8O

472.47

Darovasertib (LXS196) is a potent, selective and orally active protein kinase C (PKC) inhibitor, with IC50 values of 1.9 nM, 0.4 nM and 3.1 microM for PKCalpha, PKCtheta and GSK3beta, respectively. Darovasertib has the potential for uveal melanoma research.

NC1=C(C(NC2=C(N3CCC(C)(N)CC3)C=CC=N2)=O)N=C(C4=NC=CC=C4C(F)(F)F)C=N1

2°C to 8°C,-20°C,-80°C

12352200