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Ralimetinib dimesylate [862507-23-1]

Research Use Only
HY-13241
MedChem Express
CAS Number862507-23-1
Product group Chemicals
Estimated Purity96.97%
Molecular Weight612.74
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Ralimetinib dimesylate [862507-23-1]
  • Delivery Days Customer
    10
  • CAS Number
    862507-23-1
  • Certification
    Research Use Only
  • Estimated Purity
    96.97%
  • Molecular Formula
    C26H37FN6O6S2
  • Molecular Weight
    612.74
  • Scientific Description
    Ralimetinib dimesylate (LY2228820 dimesylate) is a selective, ATP-competitive inhibitor of p38 MAPK alpha/beta with IC50s of 5.3 and 3.2 nM, respectively. Ralimetinib (LY2228820) selectively inhibits phosphorylation of MK2 (Thr334), with no effect on phosphorylation of p38a MAPK, JNK, ERK1/2, c-Jun, ATF2, or c-Myc.
  • SMILES
    FC1=CC=C(C=C1)C2=C(NC(C(C)(C)C)=N2)C3=NC4=C(C=C3)N=C(N)N4CC(C)(C)C.OS(C)(=O)=O.OS(C)(=O)=O
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200