Prexasertib [1234015-52-1]
HY-18174
CAS Number1234015-52-1
Product group Chemicals
Estimated Purity98.03%
Molecular Weight365.39
Overview
- SupplierMedChem Express
- Product NamePrexasertib [1234015-52-1]
- Delivery Days Customer10
- CAS Number1234015-52-1
- CertificationResearch Use Only
- Estimated Purity98.03%
- Molecular FormulaC18H19N7O2
- Molecular Weight365.39
- Scientific DescriptionPrexasertib (LY2606368) is a selective, ATP-competitive second-generation checkpoint kinase 1 (CHK1) inhibitor with a Ki of 0.9 nM and an IC50 of 50=8 nM) and RSK1 (IC50=9 nM). Prexasertib causes double-stranded DNA breakage and replication catastrophe resulting in apoptosis. Prexasertib shows potent anti-tumor activity.
- SMILESNCCCOC(C=CC=C1OC)=C1C2=CC(NC3=NC=C(C#N)N=C3)=NN2
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200