Bio-Connect

Prexasertib dihydrochloride [1234015-54-3]

HY-18174A
MedChem Express
CAS Number1234015-54-3
Product group Chemicals
Estimated Purity98%
Molecular Weight438.31
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    MedChem Express
  • Product Name
    Prexasertib dihydrochloride [1234015-54-3]
  • Delivery Days Customer
    10
  • CAS Number
    1234015-54-3
  • Estimated Purity
    98%
  • Molecular Formula
    C18H21Cl2N7O2
  • Molecular Weight
    438.31
  • Scientific Description
    Prexasertib dihydrochloride (LY2606368 dihydrochloride) is a selective, ATP-competitive second-generation checkpoint kinase 1 (CHK1) inhibitor with a Ki of 0.9 nM and an IC50 of 50=8 nM) and RSK1 (IC50=9 nM). Prexasertib dihydrochloride causes double-stranded DNA breakage and replication catastrophe resulting in apoptosis. Prexasertib dihydrochloride shows potent anti-tumor activity.
  • SMILES
    NCCCOC(C=CC=C1OC)=C1C2=CC(NC3=NC=C(C#N)N=C3)=NN2.[H]Cl.[H]Cl
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200