LY2886721 [1262036-50-9]
HY-13240
CAS Number1262036-50-9
Product group Chemicals
Estimated Purity99.42%
Molecular Weight390.41
Overview
- SupplierMedChem Express
- Product NameLY2886721 [1262036-50-9]
- Delivery Days Customer10
- CAS Number1262036-50-9
- CertificationResearch Use Only
- Estimated Purity99.42%
- Molecular FormulaC18H16F2N4O2S
- Molecular Weight390.41
- Scientific DescriptionLY2886721 is a potent, selective and orally active beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor with an IC50 of 20.3 nM for recombinant human BACE1. LY2886721 is selectivity against cathepsin D, pepsin, and renin, but lacking selectivity against BACE2 (IC50 of 10.2 nM). LY2886721 can across blood-brain barrier and has the potential for Alzheimers disease treatment.
- SMILESFC1=CN=C(C=C1)C(NC2=CC=C(C([C@@]34[C@]([H])(CSC(N)=N4)COC3)=C2)F)=O
- Storage Instruction-20°C,-80°C
- UNSPSC12352200