LY294002 [154447-36-6]
HY-10108
Overview
- SupplierMedChem Express
- Product NameLY294002 [154447-36-6]
- Delivery Days Customer10
- CAS Number154447-36-6
- CertificationResearch Use Only
- Estimated Purity98%
- Molecular FormulaC19H17NO3
- Molecular Weight307.34
- Scientific DescriptionLY294002 is a broad-spectrum inhibitor of PI3K with IC50s of 0.5, 0.57, and 0.97 microM for PI3Kalpha, PI3Kdelta and PI3Kbeta, respectively. LY294002 also inhibits CK2 with an IC50 of 98 nM. LY294002 is a competitive DNA-PK inhibitor that binds reversibly to the kinase domain of DNA-PK with an IC50 of 1.4 microM. LY294002 is an apoptosis activator.
- SMILESO=C1C=C(OC2=C1C=CC=C2C3=CC=CC=C3)N4CCOCC4
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200