LY294002 [154447-36-6]

MedChem Express

LY294002 [154447-36-6]

10

154447-36-6

Research Use Only

98%

C19H17NO3

307.34

LY294002 is a broad-spectrum inhibitor of PI3K with IC50s of 0.5, 0.57, and 0.97 microM for PI3Kalpha, PI3Kdelta and PI3Kbeta, respectively. LY294002 also inhibits CK2 with an IC50 of 98 nM. LY294002 is a competitive DNA-PK inhibitor that binds reversibly to the kinase domain of DNA-PK with an IC50 of 1.4 microM. LY294002 is an apoptosis activator.

O=C1C=C(OC2=C1C=CC=C2C3=CC=CC=C3)N4CCOCC4

2°C to 8°C,-20°C,-80°C

12352200