Masitinib mesylate [1048007-93-7]
HY-10209A
CAS Number1048007-93-7
Product group Chemicals
Estimated Purity99.83%
Molecular Weight594.75
Overview
- SupplierMedChem Express
- Product NameMasitinib mesylate [1048007-93-7]
- Delivery Days Customer10
- CAS Number1048007-93-7
- Estimated Purity99.83%
- Molecular FormulaC29H34N6O4S2
- Molecular Weight594.75
- Scientific DescriptionMasitinib mesylate (AB-1010 mesylate) is a potent, orally bioavailable, and selective inhibitor of c-Kit (IC50=200 nM for human recombinant c-Kit). It also inhibits PDGFRalpha/beta (IC50s=540/800 nM), Lyn (IC50= 510 nM for LynB), Lck, and, to a lesser extent, FGFR3 and FAK. Masitinib mesylate (AB-1010 mesylate) has anti-proliferative, pro-apoptotic activity and low toxicity.
- SMILESO=C(NC1=CC=C(C(NC2=NC(C3=CC=CN=C3)=CS2)=C1)C)C4=CC=C(CN5CCN(CC5)C)C=C4.CS(=O)(O)=O
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200