Me7BIO [916440-98-7]

Name: Me7BIO [916440-98-7]
SKU: AG-MR-C0022_A27
Price: 434 EUR
Availability: InStock

AG-MR-C0022

CAS Number916440-98-7

Product group Chemicals

Estimated Purity>95% (NMR)

Molecular Weight370.2

Overview

Supplier
AdipoGen Life Sciences
Product Name
Me7BIO [916440-98-7]
Delivery Days Customer
10
CAS Number
916440-98-7
Certification
Research Use Only
Estimated Purity
>95% (NMR)
Hazard Information
Non-hazardous,Warning
Molecular Formula
C17H12BrN3O2
Molecular Weight
370.2
Scientific Description
Chemical. CAS: 916440-98-7. Formula: C17H12BrN3O2. MW: 370.2. N-methylated inactive control compound for 7BIO (Prod. No. MR-C0020). Aryl hydrocarbon receptor (AhR) agonist; causes redistribution of AhR to the nucleus. - N-methylated inactive control compound for 7BIO (Prod. No. MR-C0020). Aryl hydrocarbon receptor (AhR) agonist; causes redistribution of AhR to the nucleus.
SMILES
CN1C(=O)\C(=C2/NC3=CC=CC=C3/C/2=N\O)C2=C1C(Br)=CC=C2
Storage Instruction
2°C to 8°C,-20°C
UNSPSC
12352200

Independent actions on cyclin-dependent kinases and aryl hydrocarbon receptor mediate the anti-proliferative effects of indirubins: M. Knockaert, et al.; Oncogene 23, 4400 (2004)
Indirubin, the red shade of indigo: L. Meijer, et al. (Editors): In «Life in Progress», Station Biologique, Roscoff, 297 pp. (2006)
7-Bromoindirubin-3'-oxime induces caspase-independent cell death: J. Ribas, et al.; Oncogene 25, 6304 (2006)
An integrated computational approach to the phenomenon of potent and selective inhibition of aurora kinases B and C by a series of 7-substituted indirubins: V. Myrianthopoulos, et al.; J. Med. Chem. 50, 4027 (2007)
Cutting edge: Necrosis activates the NLRP3 inflammasome: H. Li, et al.; J. Immunol. 183, 1528 (2009)