Metergoline [17692-51-2]
HY-B1033
Overview
- SupplierMedChem Express
- Product NameMetergoline [17692-51-2]
- Delivery Days Customer10
- CAS Number17692-51-2
- CertificationResearch Use Only
- Estimated Purity99.74%
- Molecular FormulaC25H29N3O2
- Molecular Weight403.52
- Scientific DescriptionMetergoline is a serotonin (5-HT) receptor and dopamine receptors antagonist, with pKis of 8.64, 8.75 and 8.75 for 5-HT2A, 5-HT2B and 5-HT2C, respectively. Metergoline is a high-affinity ligand for the h5-HT7 receptor, with a Ki of 16 nM. Metergoline is also a reversible neural Na+ channels inhibitor. Metergoline is commonly used for the research of seasonal affective disorder, prolactin hormone regulation.
- SMILESO=C(OCC1=CC=CC=C1)NC[C@H](C[C@@]23[H])CN(C)[C@]2([H])CC4=CN(C)C5=CC=CC3=C54
- Storage Instruction-20°C,-80°C
- UNSPSC12352200