MG-132 [133407-82-6]
HY-13259
Overview
- SupplierMedChem Express
- Product NameMG-132 [133407-82-6]
- Delivery Days Customer10
- CAS Number133407-82-6
- CertificationResearch Use Only
- Estimated Purity98%
- Molecular FormulaC26H41N3O5
- Molecular Weight475.62
- Scientific DescriptionMG-132 (Z-Leu-Leu-Leu-al) is a potent proteasome and calpain inhibitor with IC50s of 100 nM and 1.2 microM, respectively. MG-132 effectively blocks the proteolytic activity of the 26S proteasome complex. MG-132, a peptide aldehyde, also is an autophagy activator. MG-132 also induces apoptosis.
- SMILESO=C(OCC1=CC=CC=C1)N[C@H](C(N[C@@H](CC(C)C)C(N[C@H](C([H])=O)CC(C)C)=O)=O)CC(C)C
- Storage Instruction-20°C,-80°C
- UNSPSC12352200