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MG-132 [133407-82-6]

Research Use Only
HY-13259
MedChem Express
CAS Number133407-82-6
Product group Chemicals
Estimated Purity98%
Molecular Weight475.62
Price on request
Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    MG-132 [133407-82-6]
  • Delivery Days Customer
    10
  • CAS Number
    133407-82-6
  • Certification
    Research Use Only
  • Estimated Purity
    98%
  • Molecular Formula
    C26H41N3O5
  • Molecular Weight
    475.62
  • Scientific Description
    MG-132 (Z-Leu-Leu-Leu-al) is a potent proteasome and calpain inhibitor with IC50s of 100 nM and 1.2 microM, respectively. MG-132 effectively blocks the proteolytic activity of the 26S proteasome complex. MG-132, a peptide aldehyde, also is an autophagy activator. MG-132 also induces apoptosis.
  • SMILES
    O=C(OCC1=CC=CC=C1)N[C@H](C(N[C@@H](CC(C)C)C(N[C@H](C([H])=O)CC(C)C)=O)=O)CC(C)C
  • Storage Instruction
    -20°C,-80°C
  • UNSPSC
    12352200