MI-136 [1628316-74-4]

MedChem Express

MI-136 [1628316-74-4]

10

1628316-74-4

Research Use Only

99.71%

C23H21F3N6S

470.51

MI-136 is an inhibitor of the menin-MLL protein-protein interaction (PPI), with an IC50 of 31 nM and a Kd of 23.6 nM. MI-136 shows to block AR signaling and has the potential for the study in castration-resistant tumors.

FC(F)(F)CC(S1)=CC2=C1N=CN=C2NC3CCN(CC4=CC=C(NC(C#N)=C5)C5=C4)CC3

2°C to 8°C,-20°C,-80°C

12352200