Quiflapon [136668-42-3]
HY-10037
CAS Number136668-42-3
Product group Chemicals
Estimated Purity98.11%
Molecular Weight587.17
Overview
- SupplierMedChem Express
- Product NameQuiflapon [136668-42-3]
- Delivery Days Customer10
- CAS Number136668-42-3
- CertificationResearch Use Only
- Estimated Purity98.11%
- Molecular FormulaC34H35ClN2O3S
- Molecular Weight587.17
- Scientific DescriptionQuiflapon (MK-591) is a selective and specific 5-lipoxygenase-activating protein (FLAP) inhibitor with an IC50 of 1.6 nM in a FLAP binding assay. Quiflapon is also a potent and orally active Leukotriene biosynthesis (LT) inhibitor, shows IC50 values of 3.1 and 6.1 nM in intact human and elicited rat PMNLs, respectively. Quiflapon induces cell apoptosis.
- SMILESO=C(O)C(C)(C)CC1=C(SC(C)(C)C)C2=C(C=CC(OCC3=NC4=CC=CC=C4C=C3)=C2)N1CC5=CC=C(Cl)C=C5
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200