Niraparib hydrochloride [1038915-64-8]
HY-10619A
CAS Number1038915-64-8
Product group Chemicals
Estimated Purity98.01%
Molecular Weight356.85
Overview
- SupplierMedChem Express
- Product NameNiraparib hydrochloride [1038915-64-8]
- Delivery Days Customer10
- CAS Number1038915-64-8
- CertificationResearch Use Only
- Estimated Purity98.01%
- Molecular FormulaC19H21ClN4O
- Molecular Weight356.85
- Scientific DescriptionNiraparib hydrochloride (MK-4827 hydrochloride) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC50s of 3.8 and 2.1 nM, respectively. Niraparib hydrochloride leads to inhibition of repair of DNA damage, activates apoptosis and shows anti-tumor activity.
- SMILESNC(C1=CC=CC2=CN(C3=CC=C([C@H]4CNCCC4)C=C3)N=C21)=O.Cl
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200