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Grazoprevir [1350514-68-9]

Research Use Only
HY-15298
MedChem Express
CAS Number1350514-68-9
Product group Chemicals
Estimated Purity99.98%
Molecular Weight766.9
Price on request
Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Grazoprevir [1350514-68-9]
  • Delivery Days Customer
    10
  • CAS Number
    1350514-68-9
  • Certification
    Research Use Only
  • Estimated Purity
    99.98%
  • Molecular Formula
    C38H50N6O9S
  • Molecular Weight
    766.9
  • Scientific Description
    Grazoprevir (MK-5172) is a selective inhibitor of Hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants, with Kis of 0.01 nM (gt1b), 0.01 nM (gt1a), 0.08 nM (gt2a), 0.15 nM (gt2b), 0.90 nM (gt3a), respectively. Grazoprevir inhibits SARS-CoV-2 3CLpro activity.
  • SMILES
    COC1=CC2=C(N=C(CCCCC[C@@H]3C[C@H]3OC4=O)C(O[C@H]5CN(C([C@H](C(C)(C)C)N4)=O)[C@H](C(N[C@@]([C@@H]6C=C)(C6)C(NS(C7CC7)(=O)=O)=O)=O)C5)=N2)C=C1
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200