ML141 [71203-35-5]
S7686
Overview
- SupplierSelleck Chemicals
- Product NameML141 [71203-35-5]
- Delivery Days Customer9
- CAS Number71203-35-5
- CertificationResearch Use Only
- Scientific DescriptionML141 (CID-2950007) is demonstrated to be a potent, selective and reversible non-competitive inhibitor of Cdc42 GTPase suitable for in vitro assays, with IC50 of 200 nM and selectivity against other members of the Rho family of GTPases (Rac1, Rab2, Rab7). ML141 is associated with an increase in p38 activation and may induce p38-dependent apoptosis/senescence. ML141 also protects neuroblastoma cells from metformin-induced apoptosis.
- UNSPSC12352200