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ML216 [1430213-30-1]

Research Use Only
HY-12342
MedChem Express
CAS Number1430213-30-1
Product group Chemicals
Estimated Purity98.07%
Molecular Weight383.32
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    ML216 [1430213-30-1]
  • Delivery Days Customer
    10
  • CAS Number
    1430213-30-1
  • Certification
    Research Use Only
  • Estimated Purity
    98.07%
  • Molecular Formula
    C15H9F4N5OS
  • Molecular Weight
    383.32
  • Scientific Description
    ML216 (CID-49852229) is a potent, selective and cell permeable inhibitor of the DNA unwinding activity of BLM helicase with IC50s of 2.98 microM and 0.97 microM for BLMfull-length and BLM636-1298, respectively. ML216 inhibits ssDNA-dependent ATPase activity of BLM with a Ki of 1.76 microM. Antitumor avtivity.
  • SMILES
    O=C(NC1=CC=C(F)C(C(F)(F)F)=C1)NC2=NN=C(S2)C3=CC=NC=C3
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200