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ML347 [1062368-49-3]

Research Use Only
HY-12274
MedChem Express
CAS Number1062368-49-3
Product group Chemicals
Estimated Purity99.85%
Molecular Weight352.39
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    ML347 [1062368-49-3]
  • Delivery Days Customer
    10
  • CAS Number
    1062368-49-3
  • Certification
    Research Use Only
  • Estimated Purity
    99.85%
  • Molecular Formula
    C22H16N4O
  • Molecular Weight
    352.39
  • Scientific Description
    ML347 (LDN193719) is a highly selective ALK1/ALK2 inhibitor. ML347 has IC50 values of 46 and 32 nM against ALK1 and ALK2, respectively, >300-fold selective over ALK3. ML347 block the phosphorylation of Smad1/5 by TGF-beta1.
  • SMILES
    COC1=CC=C(C2=CN3C(N=C2)=C(C4=C5C=CC=NC5=CC=C4)C=N3)C=C1
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200