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ML364 [1991986-30-1]

HY-100900
MedChem Express
CAS Number1991986-30-1
Product group Chemicals
Estimated Purity99.94%
Molecular Weight517.54
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    ML364 [1991986-30-1]
  • Delivery Days Customer
    10
  • CAS Number
    1991986-30-1
  • Estimated Purity
    99.94%
  • Molecular Formula
    C24H18F3N3O3S2
  • Molecular Weight
    517.54
  • Scientific Description
    ML364 is a selective ubiquitin specific peptidase 2 (USP2) inhibitor (IC50=1.1 microM) with anti-proliferative activity, which direct binds to USP2 (Kd=5.2 microM), induces an increase in cellular cyclin D1 degradation and causes cell cycle arrest. ML364 increases the levels of mitochondrial ROS and decreases in the intracellular content of ATP.
  • SMILES
    O=C(NC1=NC(C2=CC=CC=C2)=CS1)C3=CC=C(C(F)(F)F)C=C3NS(=O)(C4=CC=C(C)C=C4)=O
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200