Monomethyl auristatin E [474645-27-7]

MedChem Express

Monomethyl auristatin E [474645-27-7]

10

474645-27-7

Research Use Only

97.26%

C39H67N5O7

717.98

Monomethyl auristatin E (MMAE; SGD-1010) is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. MMAE is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) to treat several different cancer types.

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-20°C

12352200