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Motesanib [453562-69-1]

Research Use Only
HY-10228
MedChem Express
CAS Number453562-69-1
Product group Chemicals
Estimated Purity95.04%
Molecular Weight373.45
Price on request
Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Motesanib [453562-69-1]
  • Delivery Days Customer
    10
  • CAS Number
    453562-69-1
  • Certification
    Research Use Only
  • Estimated Purity
    95.04%
  • Molecular Formula
    C22H23N5O
  • Molecular Weight
    373.45
  • Scientific Description
    Motesanib (AMG 706) is a potent ATP-competitive inhibitor of VEGFR1/2/3 with IC50s of 2 nM/3 nM/6 nM, respectively, and has similar activity against Kit, and is appr 10-fold more selective for VEGFR than PDGFR and Ret.
  • SMILES
    O=C(C1=CC=CN=C1NCC2=CC=NC=C2)NC3=CC(NCC4(C)C)=C4C=C3
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200