Motesanib Diphosphate [857876-30-3]

MedChem Express

Motesanib Diphosphate [857876-30-3]

10

857876-30-3

Research Use Only

99.64%

C22H29N5O9P2

569.44

Motesanib Diphosphate (AMG 706 Diphosphate) is a potent ATP-competitive inhibitor of VEGFR1/2/3 with IC50s of 2 nM/3 nM/6 nM, respectively, and has similar activity against Kit, and is approximately 10-fold more selective for VEGFR than PDGFR and Ret.

O=C(C1=CC=CN=C1NCC2=CC=NC=C2)NC3=CC(NCC4(C)C)=C4C=C3.O=P(O)(O)O.O=P(O)(O)O

2°C to 8°C,-20°C,-80°C

12352200