Catalog number: M884400_1mg
Brand: Toronto Research Chemicals
Packing: 1 mg
Other sizes: 2 mg
5 mg
10 mg
25 mg
50 mg
Price: On Request
Expected delivery time: 21 days

Product specifications for - Myriocin

Product group: Chemicals
Category: Other
CAS No.: 35891-70-4
Molecular Formula: C21H39NO6
Molecular weight: 401,54
Melting point: >175°C (dec.)
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352200
Form supplied: White to Off-White Solid
Storage instructions: Hygroscopic, -20°C Freezer, Under inert atmosphere
Scientific information: 
Scientific info: Myriocin is a atypical amino acid and an antibiotic with potent immunosuppressant activity. Studies suggest that the immunosuppressant activity in the cytotoxic T-cell line CTTL-2 is due to apoptosis induction. Myriocin very potent inhibitor of serine palmitoyltransferase and thus blocks the synthesis ceramide, a precursor in sphingomyelin and glycosphingolipid biosynthesis. As a result Myriocin is a useful biochemical research tool for depleting cells of sphingolipids.
Additional information: 
Synonyms: M884400; (2S,3R,4R,6E)-2-Amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic Acid; [2S-(2R*,3S*,4S*,6E)]-2-Amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic Acid; (+)-Myriocin; ISP-I; NSC 177379; Thermozymocidin; (2S,3R,4R)-(E)-2-Amino-3,4-dihydroxy-2-hydroxymethyl-14-oxoeicos-6-enoic Acid