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MZ 1 [1797406-69-9]

HY-107425
MedChem Express
CAS Number1797406-69-9
Product group Chemicals
Estimated Purity95.21%
Molecular Weight1002.64
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    MZ 1 [1797406-69-9]
  • Delivery Days Customer
    10
  • CAS Number
    1797406-69-9
  • Estimated Purity
    95.21%
  • Molecular Formula
    C49H60ClN9O8S2
  • Molecular Weight
    1002.64
  • Scientific Description
    MZ 1 is a PROTAC connected by ligands for von Hippel-Lindau and BRD4. MZ 1 potently and rapidly induces reversible, long-lasting, and selective removal of BRD4 over BRD2 and BRD3. Kds of 382/120, 119/115, and 307/228 nM for BRD4 BD1/2, BRD3 BD1/2, and BRD2 BD1/2, respectively.
  • SMILES
    CC1=C(C)SC2=C1C(C3=CC=C(Cl)C=C3)=N[C@@H](CC(NCCOCCOCCOCC(N[C@@H](C(C)(C)C)C(N4[C@@H](C[C@@H](O)C4)C(NCC5=CC=C(C6=C(N=CS6)C)C=C5)=O)=O)=O)=O)C7=NN=C(C)N27
  • Storage Instruction
    -20°C,-80°C
  • UNSPSC
    12352200