Nalfurafine hydrochloride [152658-17-8]

MedChem Express

Nalfurafine hydrochloride [152658-17-8]

10

152658-17-8

99.93%

C28H33ClN2O5

513.03

Nalfurafine hydrochloride (TRK-820 hydrochloride) is a potent selective and orally active G protein-biased kappa opioid receptor (KOR)-agonist with high translational potential. Nalfurafine hydrochloride (TRK-820 hydrochloride) enhances the therapeutic potential of MOR-targeting analgesics, has the potential for uremic pruritis treatment.

O[C@@]1(CC[C@@H](N(C)C(/C=C/C2=COC=C2)=O)[C@]3([H])OC4=C5O)[C@]63C4=C(C=C5)C[C@@]1([H])N(CC7CC7)CC6.[H]Cl

2°C to 8°C,-20°C,-80°C

12352200