Necrostatin-1 [4311-88-0]

MedChem Express

Necrostatin-1 [4311-88-0]

10

4311-88-0

Research Use Only

98.69%

C13H13N3OS

259.33

Necrostatin-1 (Nec-1) is a potent and cross the blood-brain barrier necroptosis inhibitor with an EC50 of 490 nM in Jurkat cells. Necrostatin-1 inhibits RIP1 kinase (EC50=182 nM). Necrostatin-1 is also an IDO inhibitor.

O=C(C(CC1=CNC2=C1C=CC=C2)N3)N(C)C3=S

2°C to 8°C,-20°C,-80°C

12352200