NKL 22 [537034-15-4]
HY-100384
Overview
- SupplierMedChem Express
- Product NameNKL 22 [537034-15-4]
- Delivery Days Customer10
- CAS Number537034-15-4
- CertificationResearch Use Only
- Estimated Purity97.27%
- Molecular FormulaC19H23N3O2
- Molecular Weight325.4
- Scientific DescriptionNKL 22 (compound 4b) is a potent and selective inhibitor of histone deacetylases (HDAC), with an IC50 of 199 and 69 nM for HDAC1 and HDAC3, respectively. NKL 22 exhibits selectivity over HDAC2/4/5/7/8 (IC50≥1.59 microM). NKL 22 ameliorates the disease phenotype and transcriptional abnormalities in Huntingtons disease transgenic mice.
- SMILESO=C(NC1=CC=CC=C1N)CCCCCC(NC2=CC=CC=C2)=O
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200