BOLD-100 [197723-00-5]
HY-16350
CAS Number197723-00-5
Product group Chemicals
Estimated Purity98.14%
Molecular Weight502.14
Overview
- SupplierMedChem Express
- Product NameBOLD-100 [197723-00-5]
- Delivery Days Customer10
- CAS Number197723-00-5
- CertificationResearch Use Only
- Estimated Purity98.14%
- Molecular FormulaC14H12Cl4N4NaRu
- Molecular Weight502.14
- Scientific DescriptionBOLD-100 (NKP-1339; IT-139) is the first-in-class ruthenium-based anticancer agent in development against solid cancer with limited side effects. BOLD-100 induces G2/M cell cycle arrest, blockage of DNA synthesis, and induction of apoptosis via the mitochondrial pathway. BOLD-100 has a high tumor targeting potential, strongly binds to serum proteins such as albumin and transferrin and activates in the reductive tumor milieu.
- SMILES[Cl-][Ru+3]([Cl-])([Cl-])([N]1=CC2=C(N1)C=CC=C2)([N]3=CC4=C(N3)C=CC=C4)[Cl-].[Na+]
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200