NPS-2143 [284035-33-2]

MedChem Express

NPS-2143 [284035-33-2]

10

284035-33-2

Research Use Only

98.09%

C24H25ClN2O2

408.92

NPS-2143 (SB-262470A), an orally active calcilytic agent, is a selective and potent calcium ion-sensing receptor (CaSR) antagonist. NPS-2143 (SB-262470A) blocks increases in cytoplasmic Ca2+ concentrations (IC50=43 nM) elicited by activating the Ca2+ receptor in HEK 293 cells expressing the human Ca2+ receptor.

N#CC1=C(OC[C@@H](CNC(C)(CC2=CC=C3C=CC=CC3=C2)C)O)C=CC=C1Cl

2°C to 8°C,-20°C,-80°C

12352200