NPS-2143 hydrochloride [324523-20-8]
HY-10171
Overview
- SupplierMedChem Express
- Product NameNPS-2143 hydrochloride [324523-20-8]
- Delivery Days Customer10
- CAS Number324523-20-8
- CertificationResearch Use Only
- Estimated Purity99.8%
- Molecular FormulaC24H26Cl2N2O2
- Molecular Weight445.38
- Scientific DescriptionNPS-2143 hydrochloride (SB-262470A hydrochloride), an orally active calcilytic agent, is a selective and potent calcium ion-sensing receptor (CaSR) antagonist. NPS-2143 hydrochloride (SB-262470A hydrochloride) blocks increases in cytoplasmic Ca2+ concentrations (IC50=43 nM) elicited by activating the Ca2+ receptor in HEK 293 cells expressing the human Ca2+ receptor.
- SMILESN#CC1=C(OC[C@@H](CNC(C)(C)CC2=CC=C3C=CC=CC3=C2)O)C=CC=C1Cl.[H]Cl
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200